the study was carried out to develop an efficient approach for prediction the genotoxicity of carbon nanotubes. the experimental data on the bacterial reverse mutation test (ta100) on multi-walled carbon nanotubes (mwcnts) was collected from the literature and examined as an endpoint. by means of the optimal descriptors calculated with the monte carlo method a mathematical model of the endpoint...

background: essential oils from elettaria cordamomum (cardamom oil) and lavandula angustifolia (lavender oil) are used a lot in food and drug industry. cardamom oil traditionally used as spice in food now is increasingly used as diuretic, sedative and for gastrointestinal disease. lavender oil, traditionally used as an antiseptic agent, is now widely used as a relaxant, carminative, and sedativ...

The mutagenicity of ten flavonoids was assayed by the Ames test, in Salmonella typhimurium strains TA98, TA100 and TA102, with the aim of establishing hydroxylation pattern-mutagenicity relationship profiles. The compounds assessed were: quercetin, kaempferol, luteolin, fisetin, chrysin, galangin, flavone, 3-hydroxyflavone, 5-hydroxyflavone and 7-hydroxyflavone. In the Ames assay, quer...

1. The bacterial reverse mutation test uses amino-acid requiring strains of Salmonella typhimurium and Escherichia coli to detect point mutations, which involve substitution, addition or deletion of one or a few DNA base pairs (1)(2)(3). The principle of this bacterial reverse mutation test is that it detects mutations which revert mutations present in the test strains and restore the functiona...